Serveur d'exploration sur le lymphœdème

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Molecular characterization of dermal lymphatic endothelial cells from primary lymphedema skin.

Identifieur interne : 004D11 ( Main/Exploration ); précédent : 004D10; suivant : 004D12

Molecular characterization of dermal lymphatic endothelial cells from primary lymphedema skin.

Auteurs : Samuel Ogunbiyi [Royaume-Uni] ; Ganessen Chinien ; Della Field ; Julia Humphries ; Kevin Burand ; Barbara Sawyer ; Steve Jeffrey ; Peter Mortimer (dermatologue)‎ [Royaume-Uni] ; Steve Clasper ; Dave Jackson ; Alberto Smith

Source :

RBID : pubmed:21417764

Descripteurs français

English descriptors

Abstract

Lymphatic endothelial cells from primary lymphedema skin have never been cultured nor characterized. A subgroup of patients with primary lymphedema undergo surgery to bring about an improvement in their quality of life. The aim of this study was to culture and characterize LECs from the skin of these patients.

DOI: 10.1089/lrb.2010.0019
PubMed: 21417764


Affiliations:


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Le document en format XML

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<title level="j">Lymphatic research and biology</title>
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<term>Aged</term>
<term>Cell Proliferation (drug effects)</term>
<term>Cells, Cultured</term>
<term>Endothelial Cells (cytology)</term>
<term>Endothelial Cells (metabolism)</term>
<term>Endothelial Cells (pathology)</term>
<term>Female</term>
<term>Gene Expression Profiling</term>
<term>Gene Expression Regulation</term>
<term>Humans</term>
<term>Lymphedema (congenital)</term>
<term>Lymphedema (genetics)</term>
<term>Lymphedema (metabolism)</term>
<term>Lymphedema (pathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Skin (cytology)</term>
<term>Skin (metabolism)</term>
<term>Skin (pathology)</term>
<term>Vascular Endothelial Growth Factors (pharmacology)</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse de profil d'expression de gènes</term>
<term>Cellules cultivées</term>
<term>Cellules endothéliales (anatomopathologie)</term>
<term>Cellules endothéliales (cytologie)</term>
<term>Cellules endothéliales (métabolisme)</term>
<term>Facteurs de croissance endothéliale vasculaire (pharmacologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (génétique)</term>
<term>Lymphoedème (métabolisme)</term>
<term>Mâle</term>
<term>Peau (anatomopathologie)</term>
<term>Peau (cytologie)</term>
<term>Peau (métabolisme)</term>
<term>Prolifération cellulaire ()</term>
<term>Régulation de l'expression des gènes</term>
<term>Sujet âgé</term>
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<term>Vascular Endothelial Growth Factors</term>
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<term>Cellules endothéliales</term>
<term>Lymphoedème</term>
<term>Peau</term>
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<term>Lymphedema</term>
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<term>Cellules endothéliales</term>
<term>Peau</term>
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<term>Endothelial Cells</term>
<term>Skin</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Cell Proliferation</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en">
<term>Endothelial Cells</term>
<term>Lymphedema</term>
<term>Skin</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr">
<term>Cellules endothéliales</term>
<term>Lymphoedème</term>
<term>Peau</term>
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<term>Endothelial Cells</term>
<term>Lymphedema</term>
<term>Skin</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr">
<term>Facteurs de croissance endothéliale vasculaire</term>
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<term>Adult</term>
<term>Aged</term>
<term>Cells, Cultured</term>
<term>Female</term>
<term>Gene Expression Profiling</term>
<term>Gene Expression Regulation</term>
<term>Humans</term>
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<term>Middle Aged</term>
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<term>Adulte d'âge moyen</term>
<term>Analyse de profil d'expression de gènes</term>
<term>Cellules cultivées</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Mâle</term>
<term>Prolifération cellulaire</term>
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<front>
<div type="abstract" xml:lang="en">Lymphatic endothelial cells from primary lymphedema skin have never been cultured nor characterized. A subgroup of patients with primary lymphedema undergo surgery to bring about an improvement in their quality of life. The aim of this study was to culture and characterize LECs from the skin of these patients.</div>
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<name sortKey="Chinien, Ganessen" sort="Chinien, Ganessen" uniqKey="Chinien G" first="Ganessen" last="Chinien">Ganessen Chinien</name>
<name sortKey="Clasper, Steve" sort="Clasper, Steve" uniqKey="Clasper S" first="Steve" last="Clasper">Steve Clasper</name>
<name sortKey="Field, Della" sort="Field, Della" uniqKey="Field D" first="Della" last="Field">Della Field</name>
<name sortKey="Humphries, Julia" sort="Humphries, Julia" uniqKey="Humphries J" first="Julia" last="Humphries">Julia Humphries</name>
<name sortKey="Jackson, Dave" sort="Jackson, Dave" uniqKey="Jackson D" first="Dave" last="Jackson">Dave Jackson</name>
<name sortKey="Jeffrey, Steve" sort="Jeffrey, Steve" uniqKey="Jeffrey S" first="Steve" last="Jeffrey">Steve Jeffrey</name>
<name sortKey="Sawyer, Barbara" sort="Sawyer, Barbara" uniqKey="Sawyer B" first="Barbara" last="Sawyer">Barbara Sawyer</name>
<name sortKey="Smith, Alberto" sort="Smith, Alberto" uniqKey="Smith A" first="Alberto" last="Smith">Alberto Smith</name>
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<country name="Royaume-Uni">
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<name sortKey="Ogunbiyi, Samuel" sort="Ogunbiyi, Samuel" uniqKey="Ogunbiyi S" first="Samuel" last="Ogunbiyi">Samuel Ogunbiyi</name>
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<name sortKey="Mortimer, Peter" sort="Mortimer, Peter" uniqKey="Mortimer P" first="Peter" last="Mortimer">Peter Mortimer (dermatologue)‎</name>
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